Spray drying of colloidal suspensions: Coupling of particle drying and transport models with experimental validations

نویسندگان

چکیده

A numerically effective approach was developed for the modeling of spray-drying colloidal suspensions. This based on integration two models. The first is a phenomenological and radially symmetric model accounting drying single-droplets, while second employs computational fluid dynamics (CFD) simulations to account gas flow conditions atomization in spray dryer. Experiments were also conducted single suspension droplets trapped an acoustic field as well mini-spray predictions models found be reasonable agreement with experimental data, terms droplet shrinking buckling, particle yield, spatial distribution dryer mockup.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Modeling of Particle Formation during Spray Drying

A mathematical model for the evaporation of a single droplet, subjected to convective drying in a spray dryer was developed to study the transient phenomena of particle formation. During the constant-rate drying period, the governing equations and boundary conditions were transformed into a form containing Peclet number, Pe, as the main controlling parameter. A numerical solution was developed ...

متن کامل

Effects of Spray Drying and Spray Chilling on Ibuprofen Dissolution

       The formulation of hydrophobic drugs for oral drug delivery is challenging due to poor solubility, poor dissolution and poor wetting of these drugs. Consequently, the aim of this study was to improve the dissolution of a model poorly water soluble drug, ibuprofen. Microparticles containing ibuprofen were produced by spray drying and spray chilling technology in the absence/presence of a ...

متن کامل

Onset of buckling in drying droplets of colloidal suspensions.

Minute concentrations of suspended particles can dramatically alter the behavior of a drying droplet. After a period of isotropic shrinkage, similar to droplets of a pure liquid, these droplets suddenly buckle like an elastic shell. While linear elasticity is able to describe the morphology of the buckled droplets, it fails to predict the onset of buckling. Instead, we find that buckling is coi...

متن کامل

Drying of complex suspensions.

We investigate the 3D structure and drying dynamics of complex mixtures of emulsion droplets and colloidal particles, using confocal microscopy. Air invades and rapidly collapses large emulsion droplets, forcing their contents into the surrounding porous particle pack at a rate proportional to the square of the droplet radius. By contrast, small droplets do not collapse, but remain intact and a...

متن کامل

Spray-drying Cellulose Nanofibrils: Effect of Drying Process Parameters on Particle Morphology and Size Distribution

Spray-drying was chosen as an appropriately scalable manufacturing method to dry cellulose nanofibril (CNF) suspensions. Spray-drying of two different types of CNF suspensions—nanofibrillated cellulose (NFC) and cellulose nanocrystals (CNC)—was carried out using a laboratory-scale spray dryer. Effects of three spray-drying process parameters on particle morphology and particle size distribution...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Chemical engineering research & design

سال: 2021

ISSN: ['1744-3563', '0263-8762']

DOI: https://doi.org/10.1016/j.cherd.2021.04.004